Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review.

نویسندگان

  • Oriol de Solà-Morales
  • Maribel Riera
چکیده

Urea has been recently proposed for the management of hyponatremia linked to the syndrome of inappropriate secretion of ADH (SIADH). The objective of the study was to review the levels of evidence for treatment of hyponatremia associated with SIADH with urea. We performed a: systematic review of experimental trials and grading according to SIGN. No clinical trials were found. The 6 studies analysed had methodological limitations and were prone to biases. In conclusion, there is no evidence to support the efficacy of urea for the treatment of hyponatremia following SIADH.

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عنوان ژورنال:
  • Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion

دوره 61 9  شماره 

صفحات  -

تاریخ انتشار 2014